A BizTalk Developer plays a crucial role in integrating business systems within an organization, enhancing operational efficiency. Key responsibilities include designing, developing, and maintaining BizTalk applications, troubleshooting issues, and ensuring data integrity. Required skills include proficiency in BizTalk Server, .NET, and SQL. Typically working in an IT environment, they collaborate with developers, analysts, and project managers. Career progression may lead to senior developer or architecture roles, with opportunities in cloud integration and enterprise architecture.